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Iron Overload and FerriScan |
FerriScan®
FerriScan is a non-invasive technology based on MRI (Magnetic Resonance Imaging). It has a high sensitivity and specificity for the measurement of LIC over the entire range encountered in clinical practice. It can be set up on most 1.5 Tesla MRI scanners (the most common type of clinicial scanner).
FerriScan makes a map of the liver iron concentration and calculates the mean LIC. The results are unaffected by the presence of fibrosis or cirrhosis. Image data are unaffected by the presence of fibrosis or cirrhosis. Image data are acquired on an MRI scanner and are electronically transmitted to Resonance Health's data analysis centre. All data are checked to ensure correct acquisition and are then analysed under ISO 9001 quality assured standards. The LIC results are transmitted back to the originating MRI centre.
FerriScan measures a magnetic property of tissue known as R2. A calibration curve is used to convert R2 values to liver iron concentrations. Measurement have been shown to have a high degree of sensitivity and specificity for liver iron concentration measured by biopsy. FerriScan images give information on liver iron distribution. The mean LIC value given in the FerriScan report is used to guide chelation therapy.
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