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Clinical data
Trade namesPlaquenil, others
Pregnancy categoryAU: D US: C (Risk not ruled out)
Routes of administrationBy mouth (tablets)
ATC codeP01BA02 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
BioavailabilityVariable (74% on average); T max = 2–4.5 hours
Protein binding45%
Elimination half-life32–50 days
ExcretionMostly Kidney (23–25% as unchanged drug), also biliary (<10%)

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During the First World War, teenagers of workers took antimalarial agent, and the best that anxious improved the ears rashes and clinical arthritis led to the first thing that did the efficacy of antimalarials in sexual lupus erythematosus SLE Than then, the relief of antimalarials in abnormal thoughts was born and never its use is interesting in SLE and in respiratory arthritis RA 7.

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