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|Trade names||Effexor, many generics |
|License data||US DailyMed: b23637e5-d37f-41b5-ba76-fc053e903bc2|
|Pregnancy category||AU: B2 US: C (Risk not ruled out)|
|Routes of administration||by mouth|
|ATC code||N06AX16 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Protein binding||27±2% (parent compound), 30±12% (active metabolite, desvenlafaxine) |
|Metabolism||Hepatic (~50% of the parent compound is metabolised on first pass through the liver)  |
|Elimination half-life||5±2 h (parent compound for immediate release preparations), 15±6 h (parent compound for extended release preparations), 11±2 h (active metabolite)  |
|Excretion||Renal (87%; 5% as unchanged drug; 29% as desvenlafaxine and 53% as other metabolites)  |
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