Cardiac T1 Mapping and ECV Phantom (T1MES)
What is T1MES?
The T1 Mapping and ECV Standardization Program (“T1MES”) was developed to explore T1 mapping quality assurance on 1.5 and 3T magnets across numerous CMR centres worldwide. This program progressed with the development and regulatory approval of a T1MES phantom.
The T1MES Phantom was originally designed by a team of experts including cardiologists, physicists, engineers and national metrology institutes, led by Prof James C Moon (University College London) and Dr Peter Gatehouse (Imperial College London).
As part of this study, Resonance Health manufactured an initial batch of ~70 phantoms in 2015 for distribution to CMR centres worldwide engaged in the cardiovascular magnetic resonance program. Resonance Health is the sole manufacturer of these phantoms and due to continued requests from customers, it is expected that the next batch of phantoms will be manufactured in mid-2021.
Why use a T1MES phantom?
- Provides useful reassurance to centres that T1 values are unchanged for any technical reason over long periods of application;
- Enables some correction to be applied in case a sudden shift in technique is exposed by its regular scanning;
- Permits systematic inter-sequence and inter-manufacturer analyses, aiming ultimately towards corrections to a ‘standard’.
How to purchase a T1MES phantom?
If you are interested in purchasing a T1MES phantom, please register your interest now to order a phantom as part of the current or upcoming production. To place an order, please fill out the following Order Form and return it to Resonance Health directly at . One of the Resonance Health team members will contact you for further details of your order.
Spleen R2*/T2* Phantom
Resonance Health provides an analysis service to customers who require Spleen R2*/T2* analysis to quantitatively assess iron loading in the spleen. This service is for investigational use only as regulatory clearance has not been applied for, and results are to be interpreted in the context of a clinical study. As part of service setup, it is requested that sites initially scan a R2*/T2* Phantom using the spleen R2*/T2* imaging protocol and submit the data to Resonance Health to verify the parameter settings and image quality before subject scanning commences.
Cardiac T2* Phantom
Cardiac iron-loading can be assessed by MRI measurement of cardiac T2* (cardiac T2* is globally recognised as the gold standard in the assessment of cardiac iron load via T2* measurement). As part of service setup, it is requested that sites initially scan a Cardiac T2* Phantom or a Test Patient with the Cardiac T2* imaging protocol and submit the data to Resonance Health to verify the parameter settings and image quality.
FerriScan Phantom Pack
The FerriScan Phantom Pack is used as part of the setup process for FerriScan to ensure standardisation and accuracy of setup of the FerriScan protocol.
The FerriScan Phantom Pack consists of a sealed pack of vials containing a range of standardisedconcentrations of manganese chloride (MnCl2) solution. The Phantom Pack is designed to replicate the range of liver iron loading seen in clinical practice.
The FerriScan Phantom Pack is supplied as an outer box containing the “Instructions for Use: FerriScan Phantom Pack” and a sealed inner box. The inner box is scanned as part of the MRI scanner validation procedure.
A FerriScan Phantom Pack must be scanned by every MRI scanner during setup to ensure the correct sequence has been used and images are acquired correctly.