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| Clinical data | |
|---|---|
| Trade names | Provigil, Alertec, Modavigil, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a602016 |
| License data | US FDA: Modafinil |
| Pregnancy category | AU: B3 US: C [3] |
| Dependence liability | Psychological: Very low [1] Physical: Negligible [1] |
| Addiction liability | Very low to low [2] |
| Routes of administration | By mouth (tablets) [3] |
| ATC code | N06BA07 ( WHO ) |
| Legal status | |
| Legal status | AU: S4 (Prescription only) UK: POM (Prescription only) US: Schedule IV |
| Bioavailability | Not determined due to the aqueous insolubility |
| Protein binding | 62% |
| Metabolism | Hepatic (primarily via amide hydrolysis; [4] CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5 involved [5] |
| Elimination half-life | 15 hours ( R -enantiomer), 4 hours ( S -enantiomer) [6] |
| Excretion | Urine (80%) |
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